Cyclodextrins (CD) are known as the ‘gold standards’ of drug delivery systems. It was discovered about a hundred years ago and took many years to evolve and be accepted to be pharmaceutical additives or excipients. Initially CDs was used mainly for increasing stability of drugs and enhancing the aqueous solubility. Now-a-days, CDs have expanded its ability to form various non-inclusion complexes with drugs to aid in drug delivery. They are able to form aggregates by itself or with various drug combinations. These aggregates are employed in forming encapsulation, nanoparticles and micro-particles. Therefore, CDs are very versatile compounds and has the ability to change the future of drug delivery.
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